Analysis of the Progress Patterus and the Efficacy of Chemotherapy Treatment for Extramammary Pagets Disease

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  • 乳房外パジェット病の進展様式および化学療法について
  • ニュウボウ ガイ パジェットビョウ ノ シンテン ヨウシキ オヨビ カガク リョウホウ ニ ツイテ

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Abstract

From 1962 through 2005, we have had new 95 patients of extramammary paget’s disease in the National Cancer Center Hospital. Among them, we examined the average survival rate of 11 patients that underwent chemotherapy. There were six kinds of chemotherapy employed, and the most often used chemotherapy was FECOM treatment. The average survival period was 15.4 months. Furthermore, for the patients that had metastasis to more than two lymph nodes, we compared the period until the patients had remote metastasis between the groups of patients that underwent chemotherapy and those with no chemotherapy. The former group showed an extension for the period. However, the chemotherapy that we used was not uniform, and we should standardize the chemotherapy for paget’s disease. As the result of this examination, we found that about half of the patients with remote unetastasis also developed hydronephrosis, and we infered how it occurred by using the preceeding picture for the analysis of the transition course in these cases.

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