Topical Permethrin Treatment in 106 Cases of Scabies

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  • ペルメトリンクリームを用いて治療した疥癬患者106例の検討
  • ペルメトリンクリーム オ モチイテ チリョウ シタ カイセンカンジャ 106レイ ノ ケントウ

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We treated 106 patients diagnosed with scabies and 15 persons who were family members and/or caregivers with 5% permethrin cream imported for the purpose of this study. Among the 106 patients were 41 infants, 5 pregnant women, and 11 lactating women. The subjects were prescribed with one to four doses of 5% permethrin cream for application from head to toe, with a one-week interval between each application. Sixty-three cases were treated with 2 applications, 8 cases with 3 applications. Two cases required 4 applications. Thirty-three patients were treated with a combination of permethrin and another scabicide. Of the 106 patients treated, 105 patients (99.1%) were completely cured. One patient who was taking 5 mg/day of prednisolone for treatment of systemic sclerosis, had a recurrence after one and a half months. None of the treated 121 persons showed any adverse effects to the cream such as contact dermatitis. We were able to confirm in this study that 5% permethrin cream is safe and effective for the treatment of scabies in Japan; not only in adults but also in infants and in women who are pregnant or lactating.

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