Two cases of pancreatic neuroendocrine tumor and gastric gastrointestinal tumor diagnosed by endoscopic ultrasonography fine needle aspiration with cell block procedure

DOI
  • NISHIKAWA Shiori
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • TOKUMITSU Takako
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • NOGUCHI Hiroshi
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • KUROKI Eiteru
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • OHNO Akinobu
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • KAI Masahiro
    Department of Surgical Oncology and Regulation of Organ Function, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki
  • SATO Yuichiro
    Division of Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki Department of Diagnostic Pathology, University of Miyazaki Hospital, Faculty of Medicine, University of Miyazaki

Bibliographic Information

Other Title
  • 超音波内視鏡下穿刺吸引Endoscopic ultrasonography-fine needle aspiration（EUS-FNA）の細胞診検体においてセルブロック法が診断に有用であった2例

Search this article

Description

Endoscopic ultrasonography fine needle aspiration (EUS-FNA) cytology has proven to be useful for the evaluation of pancreatic tumors or gastric submucosal tumors. In the present study, utilizing the cell block procedure, we examined a diagnostic approach of endoscopic ultrasonography fine needle aspiration (EUS-FNA) cytology in two patients with these lesions. In patient 1, EUS-FNA cytology showed round cells in loose small clumps with focal rosettes or a ribbonlike structure. Immunohistostaining by the cell block procedure revealed the positivity for chromogranin A and synaptophysin in the tumor cells. We diagnosed a neuroendocrine tumor. In patient 2, EUS-FNA cytology showed spindle tumor cells with nuclear palisading. Immunohistostaining by the cell block procedure revealed the positivity for DOG-1, c-kit, and CD34 in the tumor cells. We diagnosed a gastrointestinal stromal tumor. Our findings suggest that EUS-FNA cytology with the cell block procedure offers diagnostic efficacy in patients with pancreatic tumors or gastrointestinal submucosal tumors.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top