Usefulness of the basic examination of AFP and AFP-L3 and PIVKA II using μ TASS Wako i30 in hepatocellular carcinoma diagnosis

DOI

Bibliographic Information

Other Title
  • ミュータスワコーi30によるAFP，AFP-L3，PIVKA IIの基礎的検討および肝細胞癌診断における有用性

Search this article

Description

In this report, we discuss our analytical and clinical evaluations of assays of HCC tumor markers, namely, AFP, AFP-L3, and PIVKA II, using a fully automated microfluidic immunoassay system with the laser-induced fluorescence (LIF) detector, the μ TAS Wako i30 (Wako Pure Chemical Industries, Ltd., Osaka, Japan). The robust performance of these assays on μ TAS Wako i30 satisfied the requirements for daily clinical use, and the combination of AFP-L3%, PIVKA II, and total AFP measurements resulted in higher true positive and true negative rates for HCC diagnostics than AFP measurement alone. These observations suggest that the μ TAS Wako i30 AFP-L3% and PIVKA II assay combination is a useful tool for aiding in the diagnosis of HCC.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top