Effect of the Reversed Light-Dark Cycle on Pregnant Mice

  • Mizuta Kimiko
    School of Nursing, Kagoshima Immaculate Heart University
  • Tanaka Michiko
    School of Nursing, Kagoshima Immaculate Heart University
  • Koba Fuki
    School of Nursing, Kagoshima Immaculate Heart University
  • Sunaga Kiyoshi
    Department of Physiology and Biochemistry, School of Nursing, Chiba University
  • Ishikawa Toshio
    Department of Physiology and Biochemistry, School of Nursing, Chiba University

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  • 明暗サイクル逆転が身体および妊娠に及ぼす影響

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The effects of the reversed light-dark cycle on pregnant mice were studied. Mice were divided into 3 groups ; post-C (pregnant control), post-3S (pregnant reversed light-dark cycle for 3 days), and post-7S (pregnant reversed light-dark cycle for 7 days) groups.<br> The body weight of each 3 group in pregnant groups was not different. The total diet intake during each experimental periods in pregnant groups tend to be C>7S>3S group. The total diet intake relative to body weight in control group was greater than that in post-7S group on the first and second week after pregnant periods. The loss of the fat weights in the abdominal cavity was observed with pregnant course, especially post-3S and post-7S. The plasma glucose level before delivery in post-3S group was higher than in post-C group. Although the gain of body weight in fetus on first week after pregnancy was less in post-3S group than other groups, the one before delivery tend to be greater in post-3S group than post-C group. <br> It was suggested that the reversed light-dark cycle was induced the physical stress which resulted in improved growth on fetus due to the increase of plasma glucose in post-3S group.

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