A case report of <i>Mycobacterium abscessus</i> complex detected in the otorrhea of chronic otitis media patients

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  • FUJIMURA Hiromi
    Department of Medical Laboratory, Kitasato University Hospital
  • NIHONYANAGI Shin
    Department of Medical Laboratory, Kitasato University Hospital Department of Infection Control and Prevention, Kitasato University Hospital Kitasato Institute for Life Science, Research Center for Infection Control, Kitasato University Hospital
  • OBATA Susumu
    Department of Medical Laboratory, Kitasato University Hospital
  • ADACHI Yuzuru
    Department of Medical Laboratory, Kitasato University Hospital Kitasato Institute for Life Science, Research Center for Infection Control, Kitasato University Hospital
  • MUNEKATA Shinichi
    Department of Medical Laboratory, Kitasato University Hospital
  • KANOU Yuhsaku
    Department of Laboratory Medicine, Kitasato University School of Medicine

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  • 慢性中耳炎患者の耳漏より<i>Mycobacterium abscessus</i> complexを検出した1例

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<p>We report a case of chronic otitis media caused by the Mycobacterium abscessus complex. The patient was a 72-year-old female, whose chief complaints were otalgia and otorrhea. The patient had been prescribed with ofloxacin (OFLX) otic solution and garenoxacin (GRNX) by her previous doctor and was subsequently admitted to our hospital, because her symptoms had not improved. A Gram stain of an otorrheal sample showed Gram-positive bacilli. On the basis of our suspicion of an acid-fast bacillus, we conducted Ziehl–Neelsen staining, which revealed acid-fast bacilli (Gaffky 4). The acid-fast bacilli showed rapid growth after 48 h of culture. Identification by DNA-DNA hybridization revealed the presence of M. abscessus. Combined treatment with clarithromycin (CAM) and GRNX diminished the patient’s lesion. Treatment was continued for one month, after which the patient’s symptoms were resolved. In summary, we have isolated a fast-growing M. abscessus complex in the otorrhea of a patient with chronic otitis media that was successfully treated with CAM and GRNX.</p>

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