Usefulness of detection of inducible clindamycin (CLDM) resistance in <i>Staphylococcus</i> using BD Phoenix<sup>TM</sup>

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  • INUKAI Tomomi
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital
  • KURAMAE Hitoshi
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital
  • MATSUI Natsuko
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital
  • KATO Reiko
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital
  • OKUGAWA Masaru
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital
  • NAKAMURA Kiyotada
    Department of Clinical Laboratory Pathology, Kariya Toyota General Hospital

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  • BDフェニックス​<sup>TM</sup>におけるクリンダマイシン（CLDM）誘導耐性ブドウ球菌検出の有用性

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The detection of inducible clindamycin (CLDM) resistance in Staphylococcus by the microdilution method was added to M100-S18 of the Clinical and Laboratory Standard Institute (CLSI). In response, for this revision, BD PhoenixTM Gram-Positive PMIC/ID74, a panel for gram-positive bacteria with an additional new iMLSB well, was developed for BD PhoenixTM, an automatic identification-sensitivity test system. This has allowed the detection of inducible CLDM resistance by the iMLSB test without additional tests in parallel with identification-sensitivity tests. Therefore, the basic performance of the iMLSB test was evaluated in 120 isolates of Staphylococcus. The agreement between the iMLSB test and the control test (D-test) for resistance was 99.2%, yielding superior results. The use of this panel was considered to be advantageous, allowing more rapid reporting on CLDM-inducible resistance than the conventional method.

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