Evaluation of Seven Patients with Esophageal Papilloma

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  • 食道乳頭腫7例の検討

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Upper GI endoscopic examination was performed on 8,059 patients at this center in the past 6 years, and seven of them had esophageal papillomas. The male : female ratio was 4 : 3 and the median age was 53.6 years. The chief complaint was abdominal symptoms in five cases. Two patients had undergone operations on malignant tumors.<br> The lesion was located in the middle esophagus in four cases and in the upper esophagus in three cases. A white color and granular protrusions on the surface were observed. The Yamada type III appearance was the most common, and was seen in five cases. The other two patients had a plateaushaped lesion and a conglobate lesion, respectively. Concomitant esophageal and gastric lesions included hiatus hernia in two cases, reflux esophagitis in one case, and a gastric ulcer and acute gastritis in one case.<br> Biopsies were immunostainded for human papilloma virus antibody but all the patients were negative.<br> We followd up seven of the patients, but no marked changes occurred up to 4 years. Thus, careful observation of the course without any specific interventions such as resection appears to be sufficient for this disease.

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