老若動物における赤血球の態度とビタミンEの影響 : (II) 赤血球膜脂質脂肪酸組成の加令的変化

  • 小山 恵子
    東北大学農学部栄養化学教室:(現)秋田県立脳血管研究センター
  • 木村 修一
    東北大学農学部栄養化学教室

書誌事項

タイトル別名
  • Comparative Studies of Erythrocytes Between Young and Old Rats and of the Effect of Vitamin E. : (II) THE EFFECT OF AGING ON THE FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE.
  • 老若動物における赤血球の態度とビタミンEの影響-2-赤血球膜脂質脂肪酸組成の加令的変化
  • ロウジャク ドウブツ ニ オケル セッケッキュウ ノ タイド ト ビタミン E ノ エイキョウ 2 セッケッキュウ マク シシツ シボウサン ソセイ ノ カレイテキ ヘンカ

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説明

The comparative analysis of fatty acid composition of red blood cell membranes obtained from young (6 months) and old (18 months) albino rats showed that the decrease of palmitic acid and the increase of stearic and polyunsaturated fatty acids (carbon number> 20) were demonstrated with aging. In order to separate the blood cells into fresh and aged ones, the centrifugal fractionation was applied upon the blood obtained from individual animal. It was found that the membrane lipids of aged cells on the fatty acid pattern in comparison with young cells showed the reduced palmitic acid and increased stearic and polyunsaturated fatty acids as shown in the blood cells of aged animals. Comparative studies of fatty acid pattern on the same aged cell fractions between young and old animals showed that the age-dependent changes on the cell level were more intensified in old animals. It suggests that the fatty acid composition of red blood cell membrane of old animals is different from that of young animals at the time when new-born cells are produced. (Received September 21,1970)

収録刊行物

  • ビタミン

    ビタミン 43 (1), 13-16, 1971

    公益社団法人 日本ビタミン学会

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