ビタミンB_6欠乏シロネズミ肝細胞顆粒分画の脂肪酸構成変動

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タイトル別名
  • Study on the Fatty Acid Compositions of Liver Subcellular Particles in Pyridoxine-deficient Rats
  • ビタミン B6 ケツボウ シロネズミ ギモ サイボウ カリュウ ブンカク ノ シボウサン コウセイ ヘンドウ

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Changes in the fatty acid compositions of liver subcellular particles in pyridoxine-deficient rats were investigated in the following three fractions : 1) Mitochondria : The total fat of the pyridoxine-deficient group tended to show a lower proportion of arachidonate, whereas in the phospholipid fraction, the percentage of linoleate was higher and that of arachidonate was lower in the pyridoxine-deficient group than in the pair-fed control. 2) Microsome : It was elucidated that the pyridoxine-deficient animals indicated significantly higher proportion of linoleic acid and significantly lower proportion of arachidonic acid on comparison of the total fat. In the phospholipid fraction, these changes were more strongly manifested. 3) Supernatant : In the supernatant fraction, no significant differences were found between the proportions of the fatty acids in the pyridoxine deficient and the control animals. (Received Jan. 13,1971)

収録刊行物

  • ビタミン

    ビタミン 43 (3.4), 151-155, 1971

    公益社団法人 日本ビタミン学会

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