肝疾患患者の肝臓及び血清Ubiquinone10含量

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タイトル別名
  • Ubiquinone 10 Content in the Liver and Serum in the Patients with Liver Diseases
  • カン シッカン カンジャ ノ カンゾウ オヨビ ケッセイ Ubiquinone

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説明

Ubiquinone 10 (UQ_<10>) contents in liver and serum of patients with liver diseases were examined by using a high-performance liquid chromatography according to Abe and Katsui, and the following results were obtained. 1) UQ_<10> content of hepatic cells in 4 cases having more severe than intermediate degree of degeneration and necrosis was 92.4±22.4 μg/g wet weight, which was significantly lower than 130.2±14.5 μg/g wet weight in 5 cases having no liver injury. 2) Serum UQ_<10> Content in 23 patients with liver cirrhosis was 0.42±0.14 μg/ml, which was significantly lower than those in patients with other liver diseases (acute hepatitis: 0.76±0.33, chronic hepatitis: 0.74±0.26, hepatoma: 0.64±0.43) and healthy individuals (0.68±0.15). 3) Serum UQ_<10> content in 6 patients with acute hepatitis was low at the clinically extreme stage of illness and tended to increase toward the recovering stage. 4) A significant correlation was found between the serum total cholesterol level and the serum UQ_<10> content (r=0.443, n=58).

収録刊行物

  • ビタミン

    ビタミン 54 (4), 129-136, 1980

    公益社団法人 日本ビタミン学会

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