Studies on Bifidobacterium bifidum : (I) BIOTYPES OF BIFID BACTERIA AND THE GROWTH PROMOTING ACTIVITIES OF PANTOTHENIC ACID ANALOGUES.

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  • SAKASHITA Akio
    Biological Research Laboratory of Research Laboratories, Daiichi Seiyaku Co., Ltd
  • OSHIMA Yasuo
    Biological Research Laboratory of Research Laboratories, Daiichi Seiyaku Co., Ltd

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Other Title
  • Bifidobacterium bifidumに関する研究 : (I)Biotypeとパントテン酸関連化合物の活性について
  • Bifidobacterium bifidumに関する研究-1-Biotypeとパントテン酸関連化合物の活性について
  • Bifidobacterium bifidum ニ カンスル ケンキュウ 1 Biotype ト パントテンサン カンレン カゴウブツ ノ カッセイ ニ ツイテ

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Abstract

In order to elucidate differences in growth-promoting effect of pantothenic acid (PaA) analogues between different types of bifid bacteria, growthstimulating activities of PaA, pantethine (PaSS), pantetheine-4'-phophate (P-PaSH) and CoA on total 66 strains of bifid bacteria (14 strains of type I-II, 20 of type III, 6 of type IV and 26 of type V), which were all isolated from stool of infants were assayed. In addition, peptide requirement of these strains were also determined. PaSS and P-PaSH were active for all the strains of bifid bacteria of each type. CoA was also active for all but 5 strains, whereas PaA was shown to be active for the growth of all the strains of type IV, 60% of type III, 65% of type V, and none of type I-II. Peptide was required for growth of all the strains of type I-II, 15% of type III, 23% of type V and no strain of type IV.

Journal

  • VITAMINS

    VITAMINS 42 (2), 65-72, 1970

    THE VITAMIN SOCIETY OF JAPAN

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