書誌事項
- タイトル別名
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- Uptake of Vitamin B_6 by Ascites-Sarcoma Cells : (I) UPTAKE OF PYRIDOXINE
- ピリドキシンのとりこみ
- ピリドキシン ノ トリコミ
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抄録
Uptake of pyridoxine by ascites-sarcoma cells in vitro has been investigated. Pyridoxine was uptaken against concentration gradient at low initial concentrations of pyridoxine and accumulated in the cells as phosphorylated forms of B_6. The uptake of pyridoxine by ascites-cells was greatly enhanced in the presence of glucose but it was diminished by the addition of either 2,4-dinitrophenol or sodium fluoride with glucose. 4-Deoxypyridoxine also inhibited the uptake of pyridoxine in the cells. Incubation of ascites-cells with glucose and labelled pyridoxine resulted in accumulation of labelled pyridoxine in the cells. Similarly, the accumulation was decreased by the addition of each 2,4-dinitrophenol or sodium fluoride. Furthermore, in the presence of vitamin B_6 phosphates and 4-deoxypyridoxine, labelled pyridoxine uptake was inhibited. These results support the conclusion that pyridoxine was uptaken in ascites-sarcoma cells by an energy-associated process.
収録刊行物
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- ビタミン
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ビタミン 42 (4), 222-228, 1970
公益社団法人 日本ビタミン学会
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詳細情報 詳細情報について
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- CRID
- 1390282680786952448
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- NII論文ID
- 110002850260
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- NII書誌ID
- AN00207833
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- ISSN
- 2424080X
- 0006386X
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- NDL書誌ID
- 8424896
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可