Developing “Micro bio 3D printer” and Patterning of biomaterials

Bibliographic Information

Other Title
  • マイクロバイオ 3D プリンタの開発とバイオマテリアルのパターニング
  • Developing “Micro bio 3D printer” and Patterning of biomaterials

Abstract

3D bio printing technology was promised to fabricate complex cellular tissues. By printing cells or biomaterials for scaffolds, 3D cellular tissues are fabricated. Required printing precision are several tens of micrometer order, because cell size is several tens of micrometer. But, high precision printing is difficult, because almost biomaterials are high viscosity. Therefore, the 3D bio printer which is able to print biomaterials with high precision is needed for biofabrication. In this paper, we were developed micro bio 3D printer. This printer is able to print high viscosity biomaterials with high precision. In addition, to solve a problem that printed ink was spread on the printing medium, we used gelatin gels for printing medium, because gelatin gel was low wettability. Printed ink was sodium alginate and gelatin solution. This ink was able to be gelatinized with keeping print shape. By utilizing this device and these materials, we are achieved high precision printing of biomaterials.

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