21pm3-PM024 Experimental investigation of temperature-dependent walking behavior of a DNA nanomachine

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  • Todate Yuni
    Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology
  • Komiya Ken
    Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology
  • Yamamura Masayuki
    Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology

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  • 21pm3-PM024 DNAナノマシンによる歩行動作の温度特性の検証

Abstract

In the recent years, construction of walking nanomachines that utilize the self-assembly of DNA molecules, coupled with the enzymatic reaction to cleave DNA strands in a sequence-specific manner, has been reported. However, the conventional walking DNA nanomachines have some limitations on reaction conditions due to their reaction components. For achieving the versatile nanomechanical systems that are applicable to control chemical processes, elementary DNA nanomachines are expected to work under various reaction conditions. In this study, we propose a novel type of walking DNA nanomachine, and experimentally investigated the thermal property of its elementary reaction to discuss the walking performance of the proposed DNA nanomachine.

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