P11 Effects of ultrasonic irradiation on vesicle solutions(Poster Session)

DOI
  • Nomura Masaru
    Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
  • Yamaguchi Tsuyoshi
    Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
  • Matsuoka Tatsuro
    Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
  • Koda Shinobu
    Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University

Bibliographic Information

Other Title
  • P11 ベシクル水溶液に対する超音波照射効果の研究(ポスターセッション)

Abstract

In order to clarify the effect of sonication to vesicle solution, we performed two series of experiments. Ultrasound frequency we used was 480kHz in both experiments. In the first experiment, we measured fluorescence decay of pyrene dissolved in the aqueous solution of didodecyldimethylammonium bromide (DDAB) under ultrasonic irradiation. It was found that fluorescence decay was promoted by ultrasonic irradiation. Mechanism of quenching by bromine generated from the bromide ion which was the counter ion of DDAB was suggested. It was shown that the suggested mechanism did not contradict with the experiment with additional bromine and quantitative evaluation of the chemical effect by potassium iodide (KI) dosimetry. In the second experiment, we prepared aqueous solution of dilauroyl phosphatidylcholine (DLPC) and homogenized vesicle size by using extruder. Then, we performed ultrasonic irradiation and analyzed the size distribution by dynamic light scattering (DLS). Decrease of size to a diameter around 100nm was observed up to three hours, and substantial increase of size was observed afterwards.

Journal

Details 詳細情報について

  • CRID
    1390282681029706496
  • NII Article ID
    110009710370
  • DOI
    10.20577/pamjss.15.0_67
  • ISSN
    24241512
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top