Oral Dosage Forms for Children: Acceptability and Palatability

DOI Web Site Web Site PubMed 4 References
  • Kojima Jun
    Medical and Health Resources Research Institute Perioperative Center, St. Luke's International Hospital Department of Neurological Surgery, Nihon University School of Medicine

Bibliographic Information

Other Title
  • 小児用の経口製剤：Acceptability and palatability
  • Symposium Review 小児用の経口製剤 : Acceptability and palatability
  • Symposium Review ショウニヨウ ノ ケイコウ セイザイ : Acceptability and palatability

Search this article

Abstract

  Children generally reject taking medicine which does not have a favorable shape, taste, flavor, etc. However, if a child who needs to take a medicine, rejects taking it, he might never recover from his condition. When a child is unable to take medicine orally, it is intravenously administered, and he and his caregivers then may experience stress. Syrups and suspensions are considered as favorable types of dosage forms in which to orally administer medicine to infants and children. However, they may have disadvantages such as solubility, a bad taste, portability problems or required refrigerator storage. World Health Organization (WHO) currently favors that infants and children be treated with oral solid medicines. New oral solid tablets, such as a mini-tablet, instead of liquid medicines are proposed for this group, however, there are a few reports that mini-tablets are suitable for infants and children. Palatability is one of the main elements of patient acceptability of an oral pediatric medicine. Palatability is defined as the overall appreciation of an oral medicinal product in relation to its smell, taste, aftertaste and feeling in the mouth. Design of the formulation of an oral pediatric medicine should be considered together with its palatability.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 135 (2), 245-247, 2015-02-01

    The Pharmaceutical Society of Japan

References(4)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top