Fluctuation in Macromolecular Structures and Assembly

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Other Title
  • 生体高分子の構造のゆらぎと分子集合
  • セイタイ コウブンシ ノ コウゾウ ノ ユラギ ト ブンシ シュウゴウ

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Abstract

This review describes the dynamics in macromolecular structures and assemblies. First, it is shown that kinetic studies of the hydrogen exchange reactions of proteins and nucleic acids can provide useful information on the structure and fluctuation of such biological macromolecules. Next, a new method is proposed to approach the elementary process of protein assembly. Finally, it is demonstrated that lateral diffusion of lipid haptens and membrane bound antibody has an important role for antigen-antibody reaction on a cell surface.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 101 (7), 581-595, 1981

    The Pharmaceutical Society of Japan

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