The Development of C-C Cross-Coupling Reaction of Monocarba-<i>closo</i>-dodecaborate Anion for the Synthesis of Functional Molecules
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- Kanazawa Junichiro
- Graduate School of Pharmaceutical Sciences, The University of Tokyo
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- Takita Ryo
- Graduate School of Pharmaceutical Sciences, The University of Tokyo Elements Chemistry Laboratory, RIKEN
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- Uchiyama Masanobu
- Graduate School of Pharmaceutical Sciences, The University of Tokyo Elements Chemistry Laboratory, RIKEN
Bibliographic Information
- Other Title
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- カルボランアニオンの炭素頂点におけるクロスカップリング反応の開発と機能創出
- Symposium Review : カルボランアニオンの炭素頂点におけるクロスカップリング反応の開発と機能創出
- Symposium Review : カルボランアニオン ノ タンソ チョウテン ニ オケル クロスカップリング ハンノウ ノ カイハツ ト キノウ ソウシュツ
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Abstract
A cross-coupling reaction at the carbon vertex of a monocarba-closo-dodecaborate has been developed to allow introduction of various aryl groups and other sp2/sp-hybridized carbon centers. A copper(I) complex facilitated the coupling process with a wide range of electrophiles at room temperature. The reaction was successfully used to prepare a series of C-arylated caborane anion derivatives, some of which showed potent androgen-receptor binding activity and excellent mesogenic properties.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 134 (7), 783-788, 2014-07-01
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390282681106119552
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- NII Article ID
- 130004756443
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- NII Book ID
- AN00284903
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- COI
- 1:STN:280:DC%2BC2cfovVOiuw%3D%3D
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 025628435
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- PubMed
- 24989465
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed