3-O-アルキル及び3-O-ハロアルキル-D-グルコースの合成と抗菌性

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書誌事項

タイトル別名
  • Synthesis and Antimicrobial Properties of 3-O-Alkyl and 3-O-Haloalkyl-D-glucoses
  • 3 O アルキル オヨビ 3 O ハロアルキル D グルコース ノ ゴウセイ

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抄録

A series of 3-O-alkyl and 3-O-haloalkyl-o-glucoses were prepared from 1, 2 : 5, 6-di-O-isopropylidene-α-D-glucofuranose and their antibacterial activities were evaluated. The compounds with C12 and C14-alkyl chains were the most effective in vitro antibacterial screening, among 3-O-alkyl and 3-O-haloalkyl derivatives. The 3-O-alkyl derivatives were more effective than 3-O-haloalkyl derivatives.

収録刊行物

  • 薬学雑誌

    薬学雑誌 112 (10), 723-728, 1992

    公益社団法人 日本薬学会

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