マウス精子先体反応過程における蛋白質リン酸化反応の変化

DOI Web Site Web Site 被引用文献1件

書誌事項

タイトル別名
  • Changes in Protein Phosphorylation during Acrosome Reaction of Mouse Sperm
  • マウス セイシ センタイ ハンノウ カテイ ニ オケル タンパクシツ リンサン

この論文をさがす

抄録

The changes of protein phosphorylation were analyzed during mouse sperm capacitation and acrosome reaction. Sperm adenosine 3', 5'-cyclic monophosphate (cAMP) levels were gradually elevated during capacitation period. Although 82P uptake by sperm and protein phosphorylation increased during capacitation, the phosphorylation of a 45-kDa protein remained to be relatively constant. It was also demonstrated that acrosome reaction was induced by the treatment of capacitated sperm with 0.1 mM dibutyryl cAMP, 10 mM dibutyrylguanosine 3', 5'-cyclic monophosphate, 20 μM calcium ionophore A23187 or acid-solubilized zonae pellucidae. The phosphorylation of a 45-kDa protein was augmented during the acrosome reaction induced by such agents. These results suggest that changes in protein phosphorylation might be involved in the regulation of mouse sperm capacitation and acrosome reaction.

収録刊行物

  • 薬学雑誌

    薬学雑誌 110 (5), 325-331, 1990

    公益社団法人 日本薬学会

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ