Antipyretic Effects of Traditional Chinese Medicines in Bacterial Endotoxin-Induced Febrile Rabbits

DOI Web Site Web Site

Bibliographic Information

Other Title
  • 細菌内毒素による発熱ウサギを用いた漢方方剤の解熱作用の検討
  • サイキンナイ ドクソ ニ ヨル ハツネツ ウサギ オ モチイタ カンポウ ホウ

Search this article

Abstract

The antipyretic effects of oral administration of eight traditional Chinese medicines (dried extracts) were tested in febrile rabbits injected with bacterial pyrogen, lipopolysaccharide (LPS) 0.05 μg/kg (i.v.). The traditional Chinese medicines were given 0.6-2 g/10 ml/kg (p.o.) simultaneously with LPS. The most potent antipyretic effect was observed in Dai-jyoki-to (Tachen-chi-tang). The moderate antipyretic effects were observed in Tokisyakuyaku-san (Tang-kuei-shao-yao-san) and Syo-saiko-to (Hssiao-chai-hutang). Koso-san (Hsiang-su-san), Oren-gedoku-to (Huang-lien-chieh-tu-tan), Gorei-san (Wu-ling-san), Kakkon-to (Ko-ken-tang) and Byakkoka-ninjin-to (Pai-hu-chia-jen-sheng-tang) showed no effects.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 112 (2), 129-134, 1992

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

Report a problem

Back to top