Diethylaminoethylation of Some Aromatic Primary Amines

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Other Title
  • 芳香族第一級アミン基のヂエチルアミノエチル化について (津田試薬の合成について)

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Description

Synthesis of β-diethylaminoethyl-α-naphthylamine, a coloration reagent for microdetermination of sulfa drugs, was attemted. Reaction of α-naphthylamine and diethylaminoethyl chloride in pyridine by heating for a few hours gave the desired compound in a 56% yield. By the same procedure of aniline, o-toluidine and p-phenetidine, diethylaminoethyl derivatives were obtained in 40-50% yield.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 71 (12), 1496-1497, 1951

    The Pharmaceutical Society of Japan

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