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- 橘川 郁男
- 塩野義製薬株式会社研究所
書誌事項
- タイトル別名
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- Synthesis of Bulbocapnine
- Bulbocapnine ノ ゴウセイ
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説明
The racemic compound of bulbocapnine (I), the tertiary phenolic base of aporphine type obtained from Corydalis tuberosa DC. (Papaveraceae), was synthesized by the route shown in Chart 1. This dl-bulbocapnine (I), m.p. 213-214°, was derived to l-bulbocapnine d-tartrate by the application of d-tartaric acid, and l-bulbocapnine (Ib), m.p. 202-203°, was obtained in pure state from this d-tartrate. The application of l-tartaric acid to dl-bulbocapnine (I) gave d-bulbocapnine l-tartrate, from which pure d-bulbocapnine (Ia), m.p. 201-203°, was obtained.<br>Application of methyl iodide to d- and l-bulbocapnines so obtained afforded the quaternary phenolic base of aporphine type, d- and l-bulbocapnine methiodides (XIa and XIb), m.p. 253-254° (decomp.), and the methiodides were converted by silver chloride into respective methochlorides (XIIa and XIIb), m.p. 226-228° (decomp.).
収録刊行物
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- 薬学雑誌
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薬学雑誌 79 (10), 1244-1248, 1959
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282681163550080
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- NII論文ID
- 40018545029
- 130007283663
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 9210536
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可