Pharmacological Studies on Bamboo Grass. III. Effects on Cardiovascular and Isolated Organs of Water-Soluble Fraction extracted from Sasa albomarginata MAKINO et SHIBATA (Bambusaceae)

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Other Title
  • クマザサの薬理学的研究(第3報)クマザサ水可溶分面の循環器ならびに摘出臓器に対する作用
  • クマザサの薬理学的研究-3-クマザサ水可溶分画の循環器ならびに摘出臓器に対する作用(ノート)
  • クマザサ ノ ヤクリガクテキ ケンキュウ 3 クマザサミズ カヨウ ブンカク

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Pharmacological effect of water-soluble fraction (crude Folin) extracted from Sasa albomarginata MAKINO et SHIBATA (Bambusaceae) was examined in small animals. Crude Folin showed a prolonged hypotension and a decrease in heart rate in anesthetized rats. In the isolated frog heart and the isolated rat atrium, a negative inotropic effect was exhibited, and in the isolated rat aortic strip, a slight relaxation was observed by the crude fraction. Antagonistic effect was also observed against contraction induced by acetylcholine in the isolated rat fundus strip and against contraction induced by nicotine in the isolated guinea-pigileum. Further, crude Folin showed a slight depression of the pepsin activity in the rat gastric content.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 98 (10), 1436-1440, 1978

    The Pharmaceutical Society of Japan

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