On the Constituents of the Fruit of Arctium lappa

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  • 牛蒡子の成分について
  • ゴボウ コ ノ セイブン ニ ツイテ

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Abstract

From the fruits of Arctium lappa L. (Japanease name"goboshi, ""akujitsu, "or "dairikishi"), two new sesquilignan derivatives, AL-D and AL-F, were isolated along with arctin, arctigenin, and matairesinol. From spectroscopic and chemical investigations, the structure of AL-D was elucidated as 2-[2-(3-methoxy-4-hydroxy) phenyl-3-hydroxymethyl-7-methoxy-2, 3-dihydrobenzofuran-5-yl] methyl-3-(3-methoxy-4-hydroxy)-benzyl-buthyrolactone [I] or 2-(3-methoxy-4-hydroxy) benzyl-3-[2-(3-methoxy-4-hydroxy)-phenyl-3-hydroxymethyl-7-methoxy-2, 3-dihydrobenzofuran-5-yl] methyl-buthyrolactone [II]. AL-F was found to be a stereoisomer of AL-D.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 96 (12), 1492-1493, 1976

    The Pharmaceutical Society of Japan

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