On the Reaction of 2-Cyanopyridine with Hydrazine

DOI Web Site Web Site

Bibliographic Information

Other Title
  • 2-シアノピリジンとヒドラジンの反応について
  • 2-シアノピリジン ト ヒドラジン ノ ハンノウ ニ ツイテ

Search this article

Description

Reaction of 2-cyanopyridine with hydrazine was examined using picolinic acid amidrazone (IV) which is an intermediate of this reaction. When the ethanol solution of IV was heated under reflux in nitrogen atmosphere, 3, 6-di (2-pyridyl)-1, 2-dihydro-1, 2, 4, 5-tetrazine (I) and 1, 2-bis (pyridine-2-formimidoyl) hydrazine (III) were obtained. The quantitative study of the reaction suggested that I was not formed via III but they were produced simultaneously. Application of oxygen during refluxing of ethanol solution of IV gave I, III, 3, 6-di (2-pyridyl)-1, 2, 4, 5-tetrazine (V) and 2-pyridinecarboxaldehyde pyridine-2-forminidoylhydrazone (VI).

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 92 (3), 275-277, 1972

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

Report a problem

Back to top