A prospective comparison of the epidemiological and clinical characteristics of pandemic (H1N1) 2009 influenza A influenza virus and seasonal influenza A viruses in Guangzhou, South China in 2009

DOI Web Site PubMed 被引用文献2件 参考文献19件
  • Yang Zi-feng
    Macau University of Science and Technology, Faculty of Chinese Medicine The First Affiliated Hospital of Guangzhou Medical College, Division of Clinical Virology of State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Zhan Yang-qing
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Chen Rong-chang
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Zhou Rong
    The First Affiliated Hospital of Guangzhou Medical College, Division of Clinical Virology of State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Wang Yu-tao
    The First Affiliated Hospital of Guangzhou Medical College, Division of Clinical Virology of State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Luo Yi
    Guangdong Provincial Hospital of Traditional Chinese Medicine, Emergency Department
  • Jiang Mei
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Li Ji-qiang
    Guangdong Provincial Hospital of Traditional Chinese Medicine, Emergency Department
  • Qin Sheng
    The First Affiliated Hospital of Guangzhou Medical College, Division of Clinical Virology of State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Guan Wen-da
    The First Affiliated Hospital of Guangzhou Medical College, Division of Clinical Virology of State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Lai Ke-fang
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Wen Huan-lian
    Department of Infectious Disease of The First Affiliated Hospital of Guangzhou Medical College
  • Liang Zeng-wei
    Department of Infectious Disease of The First Affiliated Hospital of Guangzhou Medical College
  • Li Li
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)
  • Zhong Nan-shan
    Department of Respiratory Medicine of The First Affiliated Hospital of Guangzhou Medical College, State Key Laboratory of Respiratory Disease (Guangzhou Medical University)

書誌事項

タイトル別名
  • A Prospective Comparison of the Epidemiological and Clinical Characteristics of Pandemic (H1N1) 2009 Influenza A Virus and Seasonal Influenza A Viruses in Guangzhou, South China in 2009

この論文をさがす

抄録

Comparisons of the clinical characteristics of contemporaneous pandemic (H1N1) 2009 influenza A virus (A(H1N1)pdm09)- and seasonal influenza viruses-infected patients are important for both clinical management and epidemiological studies. A prospective multicenter observational study was conducted using a preestablished sentinel surveillance system in Guangzhou, China during 2009. In this study, the clinical presentations of patients with either acute respiratory infection or community-acquired pneumonia were recorded, and nasopharyngeal swab samples were collected for detection of respiratory virus strains using cell cultures or real-time reverse transcription/real-time polymerase chain reaction. Comparisons of the clinical features between A(H1N1)pdm09- and seasonal influenza viruses-infected patients were conducted accordingly. Of the 1,498 patients examined, 265 tested positive for A(H1N1)pdm09, 286 were positive for seasonal influenza A viruses, and 137 for influenza B viruses. The predominant virus was influenza B before the emergence of A(H1N1)pdm09 (epidemiological week [EW] 1–EW 21); then, predominantly non-A(H1N1)pdm09 influenza A and, later, A(H1N1)pdm09, which peaked in EW 46. Compared with the common seasonal influenza-infected patients, A(H1N1)pdm09-infected patients were younger, and had a higher proportion of these patients reported prior contact with infected individuals (P < 0.001, by χ2 test). However, few significant differences were observed in clinical symptoms and severity among any of the infections caused by the different influenza A strains. Our hospital-based network served as a useful source of information during A(H1N1)pdm09 monitoring. Viral distribution in Guangzhou was characterized by a sharp rise in A(H1N1)pdm09-infected patients in September 2009. Similar to seasonal influenza A-infected cases, A(H1N1)pdm09 cases had a very small proportion of severe cases.

収録刊行物

被引用文献 (2)*注記

もっと見る

参考文献 (19)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ