Detection and Serotyping of Human Adenoviruses from Patients with Influenza-Like Illness in Mongolia
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- Tohma Kentaro
- Department of Virology, Tohoku University School of Medicine
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- Bayasgalan Namuuntsetsegiin
- Department of Virology, National Center of Communicable Diseases
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- Suzuki Akira
- Department of Virology, Tohoku University School of Medicine
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- Darma Badarchiin
- Department of Virology, National Center of Communicable Diseases
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- Oshitani Hitoshi
- Department of Virology, Tohoku University School of Medicine
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- Nymadawa Pagbajabyn
- Department of Virology, National Center of Communicable Diseases Mongolian Academy of Medical Sciences
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Abstract
Human adenoviruses (HAdVs) are responsible for approximately 5%–10% of acute respiratory infections. The serotypes of commonly detected respiratory HAdV in Asian countries are diverse. However, there are no well-documented reports of circulating HAdV serotypes in Mongolia. Between January 2010 and May 2011, 1,950 influenza-negative samples from patients with influenza-like illness, including eye swabs from patients with eye symptoms, were screened for HAdV, and 40 samples (2.1%) were positive for HAdVs. Among these 40 samples, 31 samples were positive for the hexon gene used in phylogenetic analysis, as determined by PCR. We identified 7 different serotypes. We constructed the phylogenetic trees of HAdV-B7 and HAdV-B3, the 2 most commonly detected serotypes in this study. All detected HAdV-B7 and -B3 Mongolian strains had identical sequences. HAdV-D8, known to be associated with epidemic keratoconjunctivitis (EKC), was detected from nasopharyngeal and eye swabs. There was no difference between the amino acid sequences of the hexon and fiber genes that may affect tissue tropism in Mongolian strains and those in EKC-causing strains.
Journal
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 65 (4), 289-294, 2012
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
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Details 詳細情報について
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- CRID
- 1390282681218023808
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- NII Article ID
- 130001931824
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- NII Book ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL BIB ID
- 023840457
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- PubMed
- 22814149
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed