EXPERIMENTALLY-INDUCED AGAMMAGLOBULINEMIA IN JAPANESE QUAILS
-
- YOSHIKAWA YASUHIRO
- <I>Department of Measles Virus, National Institute of Health</I>
-
- ITO MASAHIRO
- <I>Division of Animal Research, Faculty of Medicine, University of Tokyo</I>
-
- YAMANOUCHI KAZUYA
- <I>Department of Measles Virus, National Institute of Health</I>
Bibliographic Information
- Other Title
-
- Experimentally induced agammaglobulinem
Search this article
Abstract
Induction of agammaglobulinemia in Japanese quails was attempted by various procedures of bursectomy (BX) including hormonal BX (H-BX) with testosterone, surgical BX (S-BX), chemical BX (C-BX) with cyclophosphamide and irradiation with γ-ray. Immunosuppressive effect of BX was evaluated by antibody production in response to immunization with bovine serum albumin and sheep red blood cells, by the level of natural antibody, and by the amount of immunoglobulins in sera. As a result, two procedures, i.e. combination of H-BX, S-BX, and C-BX and combination of H-BX, S-BX and irradiation were found to induce most frequently complete aggamaglobulinemia in which neither immunoglobulin nor antibody production was detected. Mechanisms of immunosuppression of these BX procedures were discussed from the morphological aspect of development of the bursa.
Journal
-
- Japanese Journal of Medical Science and Biology
-
Japanese Journal of Medical Science and Biology 31 (2), 119-134, 1978
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
- Tweet
Details 詳細情報について
-
- CRID
- 1390282681218136448
-
- NII Article ID
- 130003953266
-
- NII Book ID
- AA1132885X
-
- COI
- 1:STN:280:DyaE1c3ksV2ltA%3D%3D
-
- ISSN
- 18842828
- 00215112
-
- NDL BIB ID
- 1937236
-
- PubMed
- 682369
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed