Acetylcholinesterase in Insecticide Resistant Culex tritaeniorhynchus: Characteristics Accompanying Insensitivity to Inhibitors
書誌事項
- タイトル別名
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- Acetylcholinesterase in Insecticide Res
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説明
The acctylcholinesterase (AChE) of the Toyama strain (Toyama) of Culex tritaeniorhynchus showed extremely low sensitivity to various kinds of organophosphorus insecticides (OPs) and carbamates. Several characteristics of the AChE of Toyama have been tested and compared with those of the OP susceptible strain (Taiwan). The AChE of Toyama is different from that of Taiwan in many respects. It showed no clear optimum pH and substrate concentration (AChE of Taiwan had both the optimum pH and substrate concentration). Affinity for ACh was high (Km value for ACh is 0.65 times the value of Taiwan), but affinity for the substrate declined significantly for acetylthiocholine and propionylthiocholine. I50 values for OPs were extremely high (66.1-7, 079 times the value for Taiwan), and those for carbamates were also higher than those for Taiwan (20.4-112 times). These results suggest that the structure of the AChE of Toyama has changed to an ACh specific form which has a remarkably lower affinity to the OP compounds.
収録刊行物
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- Ａｐｐｌｉｅｄ Ｅｎｔｏｍｏｌｏｇｙ ａｎｄ Ｚｏｏｌｏｇｙ
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Ａｐｐｌｉｅｄ Ｅｎｔｏｍｏｌｏｇｙ ａｎｄ Ｚｏｏｌｏｇｙ 32 (1), 37-44, 1997
日本応用動物昆虫学会
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詳細情報 詳細情報について
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- CRID
- 1390282681220352896
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- NII論文ID
- 110001103573
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- NII書誌ID
- AA00543238
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- COI
- 1:CAS:528:DyaK2sXhvFOjtr0%3D
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- ISSN
- 1347605X
- 00036862
- http://id.crossref.org/issn/00036862
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- NDL書誌ID
- 4153809
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
