コレラ菌のDihydroxymethyl-furatrizine (Panfuran-S) に対する感受性

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タイトル別名
  • SENSITIVITY OF<I>VIBRIO CHOLERAE</I> (BIOTYPE <I>EL TOR</I>) TO PANFURAN-S
  • コレラシ ノ Dihydroxymethyl-furatrizine Panfuran-S ニ タイスル カンジュセイ 1 1941ネン カラ 1971ネン ニ ブンリ サレタ El Tor カタ コレラキン ノ ヤクザイ カンジュセイ
  • 1. DRUG SENSITIVITIES OF <I>V. CHOLERAE</I> ISOLATED DURING THE PERIOD OF 1940-1971
  • (1) 1941年から1971年に分離された<I>El Tor</I>型コレラ菌の薬剤感受性

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説明

Drug sensitivities were examined by the plate dilution method for 103 strains of Vibrio cholerae (biotype El Tor), of which 72 and 31 strains had been isolated in India in 1940 and in Philippines in the period of 1969 to 1971 respectively. Strains resistant to chloramphenicol and/or tetracycline were found to be simultaneously resistant to streptomycin and sulfonamide, i. e. multiple drug resistant strains. Whereas, strains resistant to streptomycin or sulfonamide were not only multiple resistant but also single resistant strains. It was noteworthy that all tested strains of V. cholerae (biotype El Tor) were highly sensitive to Panfuran-S, regardless of multiple resistant or single resistant strains to other drugs.<BR>It was confirmed that inoculum size of the test bacteria affected markedly on the minimum growth inhibitory concentrations of sulfonamide and Panfuran-S but not of chloramphenicol, tetracycline and streptomycin.

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