尿路感染症に対する3', 4'-Dideoxykanamycin Bの基礎的, 臨床的研究

DOI Web Site

書誌事項

タイトル別名
  • BASIC AND CLINICAL STUDIES ON 3', 4'-DIDEOXYKANAMYCIN B IN URINARY-TRACT INFECTIONS
  • ニョウロ カンセンショウ ニ タイスル 3 , 4 -Dideoxykanamycin B ノ キソテキ , リンショウテキ ケンキュウ

この論文をさがす

抄録

The blood level of 3', 4'-dideoxykanamycin B (DKB) in healthy adults who were given 50 mg, i. m., reached maximum of 12. 6 mcg/ml 30 minutes after administration, and the level was 3.26 mcg/ml 4 hours after dosing, showing a good evidence that the drug is smoothly distributed in blood and maintained at high concentrations for a prolonged period.<BR>Total urinary recovery of DKB during the period of 24 hours after administration was 60.2%. Bacteriologically, DKB was effective against gram-negative bacteria, especially E. coli, Pseudomonas and Proteus vulgaris.<BR>Patients with complicated urinary-tract infections responded to DKB treatment.<BR>No noteworthy adverse effects were recognized.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ