MORPHOLOGICAL ALTERATIONS IN <I>ESCHERICHIA COLI</I> NO.29, <I>PROTEUS MORGANH</I> NO.101 AND <I>SERRATIA MARCESCENS</I> T-55 EXPOSED TO CEFOXITIN
-
- NISHINO TAKESHI
- Department of Microbiology, Kyoto College of Pharmacy
-
- TOBE KENSUKE
- Department of Microbiology, Kyoto College of Pharmacy
-
- YAMAGISHI JUN-ICHI
- Department of Microbiology, Kyoto College of Pharmacy
-
- NAKAZAWA SHOZO
- Department of Microbiology, Kyoto College of Pharmacy
Bibliographic Information
- Other Title
-
- Cefoxitinによる<I>Escherichia coli, Proteus morganii, Serratia marcescens</I>の形態変化について
- Cefoxitin ニヨル Escherichia coli Proteus
Search this article
Abstract
The effects of cefoxitin (CFX) on the morphology of E. coli No.29, Pr. morganii No.101 and Ser. marcescens T-55 were examined by the phase contrast microscope and the scanning electron microscope. The following results were obtained:<BR>1) CFX induced filament formations and spheroplast-like structures at the minimum inhibitory concentration (MIC) with E. coli No.29.<BR>These morphological alterations of E. coli No.29, treated with CFX, were similar to those with cephalothin (CET) and cefazolin (CEZ), used as control drugs.<BR>2) Spheroplast formations and cell lysis were observed when CFX was allowed to act on Pr. morganii No.101 and Ser. marcescens T-55 (β-lactam antibiotic resistant strain). When treated with CET and CEZ, most cells grew similarly to the untreated controls of Pr. morganii No.101 and Ser. marcescens T-55.
Journal
-
- CHEMOTHERAPY
-
CHEMOTHERAPY 26 (Supplement1), 88-99, 1978
Japanese Society of Chemotherapy
- Tweet
Details 詳細情報について
-
- CRID
- 1390282681257428864
-
- NII Article ID
- 130004192386
-
- NII Book ID
- AN00186653
-
- ISSN
- 18845894
- 00093165
-
- NDL BIB ID
- 1931413
-
- Data Source
-
- JaLC
- NDL
- CiNii Articles
-
- Abstract License Flag
- Disallowed