THE CLINICAL EXPERIMENT OF HBK IN EXTERNAL EYE DISEASES AND THE PENETRATION INTO THE AQUEOUS AND TEAR OF HUMAN EYES

DOI
  • TOKUDA HISAYA
    Department of Ophthalmology, Kyorin University, School of Medicine
  • YATA KOJI
    Department of Ophthalmology, Kyorin University, School of Medicine
  • SHIMIZU CHIHIRO
    Department of Ophthalmology, Kyorin University, School of Medicine

Bibliographic Information

Other Title
  • 眼科領域におけるHBKの臨床的・実験的検討

Abstract

Four cases of external eye diseases (meibomitis and orbital phlegmone) were cured all after 3-4 days (100%).<BR>The penetration of HBK into the aqueous of 26 human cases and tear in 23 cases were examined, simultaneously with serum at O.25, O.5, 1, 2, 3, 4 and 6 hour after the i. m. injection of 100mg.<BR>The peak of aqueous level was O.13μg/ml (2 hour after) and detectable after 6 hour.<BR>The peak of tear level was over 1.0μg/ml (1/2-3 hour after) and half time in serum was 2.89 hour. This level was considered effective to the external eye infections by S. aureus and others.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 34 (Supplement1), 662-664, 1986

    Japanese Society of Chemotherapy

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