CLINICAL STUDIES OF EFFICACY COMPARISON BETWEEN CEFTEZOLE AND CEFAZOLIN IN PNEUMONIA

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  • NAKAGAWA KEIICHI
    Department of Internal Medicine, Tokyo Kyosai Hospital
  • KABE JUNZABURO
    Department of Internal Medicine, Tokyo Kyosai Hospital
  • WATANABE KENTARO
    Department of Internal Medicine, Tokyo Kyosai Hospital
  • KATO YASUMICHI
    The Second Department of Internal Medicine, Hokkaido University, School of Medicine
  • SAITO AKIRA
    The Second Department of Internal Medicine, Hokkaido University, School of Medicine
  • NAKAYAMA ICHIRO
    The Second Department of Internal Medicine, Hokkaido University, School of Medicine
  • KIMURA TAKESHI
    The Second Department of Internal Medicine, Iwate Medical University, School of Medicine
  • AMANO KATSUHIKO
    The Second Department of Internal Medicine, Iwate Medical University, School of Medicine
  • GOTO KOOJI
    Clinic of Internal Medicine, Tsuruoka Municipal Shonai Hospital
  • YAMASAKU FUSANOSUKE
    The Second Department of Internal Medicine, Niigata University, School of Medicine
  • IWANAGA MORITO
    The Second Department of Internal Medicine, Niigata University, School of Medicine
  • WATANABE MAKOTO
    The Second Department of Internal Medicine, Niigata University, School of Medicine
  • SEKINE OSAMU
    Department of Internal Medicine, Shinrakuen Hospital
  • USUDA YOSHIMARU
    Department of Internal Medicine, Shinrakuen Hospital
  • UEDA YASUSHI
    The Third Department of Internal Medicine, The Jikei University, School of Medicine
  • MATSUMOTO FUMIO
    The Third Department of Internal Medicine, The Jikei University, School of Medicine
  • SAITO ATSUSHI
    The Third Department of Internal Medicine, The Jikei University, School of Medicine
  • SHIMIZU KIHACHIRO
    The First Department of Internal Medicine, University of Tokyo, School of Medicine
  • MASHIMO KEIMEI
    Department of Internal Medicine, Institute of Medical Science, University of Tokyo
  • FUKAYA KAZUFUTO
    Department of Internal Medicine, Institute of Medical Science, University of Tokyo
  • KUNII OTOHIKO
    Department of Internal Medicine, Institute of Medical Science, University of Tokyo
  • KITAMOTO OSAMU
    Department of Internal Medicine, Kyorin University, School of Medicine
  • KOBAYASHI HIROYUKI
    Department of Internal Medicine, Kyorin University, School of Medicine
  • SHIMADA KAORU
    Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital
  • KATSU MASATAKA
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • FUJIMORI IPPEI
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • SHIMADA SANAKA
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • GOMI KENICHI
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • FUKUSHIMA KOKICHI
    The First Department of Internal Medicine, Yokohama City University, School of Medicine
  • ITO AKIRA
    The First Department of Internal Medicine, Yokohama City University, School of Medicine
  • YAMAMOTO TOSHIYUKI
    The First Department of Internal Medicine, Nagoya City University, School of Medicine
  • SHIOTA KENZO
    The First Department of Internal Medicine, Osaka City University, School of Medicine
  • MIKI FUMIO
    The First Department of Internal Medicine, Osaka City University, School of Medicine
  • OKUBO HIROSHI
    The First Department of Internal Medicine, Kansai Medical University
  • OKAMOTO YURUKO
    The First Department of Internal Medicine, Kansai Medical University
  • UBA FUMIHIKO
    The First Department of Internal Medicine, Kansai Medical University
  • MAEHARA KEIGO
    The First Department of Internal Medicine, Kansai Medical University
  • KAWAMORI YUZO
    Department of Internal Medicine, Senboku National Hospital
  • NISHIZAWA NATSUO
    Department of Internal Medicine, Senboku National Hospital
  • TSUJIMOTO TAKEHIRO
    Department of Internal Medicine, Hosigaoka Welfare Pension Hospital
  • YAMAGUCHI SAKIMORI
    Department of Internal Medicine, Hosigaoka Welfare Pension Hospital
  • OYAMA KAORU
    Department of Internal Medicine, Toyama Prefectural Central Hospital
  • SOEZIMA RINZO
    Department of Internal Medicine, Kawasaki Medical College
  • KIMURA NAOMI
    Department of Internal Medicine, Hiroshima Red Cross Hospital
  • KURIMURA OSAMU
    Department of Internal Medicine, Kure National Hospital
  • HARA KOHEI
    The Second Department of Internal Medicine, Nagasaki University, School of Medicine
  • NASU MASARU
    The Second Department of Internal Medicine, Nagasaki University, School of Medicine
  • NAKATOMI MASAO
    The Second Department of Internal Medicine, Nagasaki University, School of Medicine

Bibliographic Information

Other Title
  • CeftezoleとCefazolinの肺炎に対する薬効比較に関する臨床的研究
  • Ceftezole ト Cefazolin ノ ハイエン ニ タイスル ヤッコ

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Description

The present authors have carried out a double blind test on the patients of pneumonia hospitalized in 23 institutions as indicated in Table 1, to compare clinical effects of ceftezole (CTZ) with those of cefazoin (CEZ). Each drugs was administered intramuscularly at a daily dose of 2 g for 7-14 days, and both therapeutic efficacy and utility were investigated by comparison.<BR>1. Prescribed dose of the drug was administered for 7-14 days and transfer of chest X-ray finding could be judged in 117 cases of pneumonia. Comparison was made between two drugs of CTZ and CEZ, and the following conclusions were obtained.<BR>1) No significant difference was observed in the therapeutic effects on 7th or 14th day after administration between 53 cases of CTZ group and 64 cases of CEZ group.<BR>2) No significant difference was shown between the utility of two drugs in 117 cases of pneumonia.<BR>2. Investigation was performed on 167 cases, excluding the cases of whom a bacterial pneumonia was suspected at first visit and a prescribed treatment was commenced, however an against-rule or non-objective disease was confirmed distinctly after the examination completion. As a result, no significant difference was demonstrated in therapeutic effects between two drugs.<BR>3. No difference was noticed between the side-effects of two drugs in total 182 cases including the above 117 cases.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 24 (4), 926-945, 1976

    Japanese Society of Chemotherapy

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