書誌事項
- タイトル別名
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- PHARMACOKINETICS AND CLINICAL EVALUATION OF CINOXACIN IN URINARY TRACT INFECTIONS
- ニョウロ カンセンショウ ニ タイスル Cinoxacin ノ キソテキ リン
この論文をさがす
抄録
Cinoxacin, a new synthetic antibacterial agent, was evaluated on pharmacokinetics in healthy adults and clinical effect for urinary tract infections.<BR>1) The mean peak serum concentration in 6 healthy male adults, when each subject received a single 400mg oral dose of cinoxacin, was 8.5μg/ml with bioassay. Fifty-two per cent of the drug was excreted in the urine within the first 8 hours.<BR>2) Its clinical effect for 47 cases of acute simple cystitis included 34 excellent effective cases, 12 moderate effective cases and 1 poor effective case, the overall effective rate being 97.9%. The clinical effect for 14 chronic complicated cystitis contained 2 excellent effective cases, 5 moderate effective cases and 7 poor effective cases, the rate of effectiveness being 50%.<BR>3) As for side effects, slight epigastralgia was observed in 2 cases.
収録刊行物
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- CHEMOTHERAPY
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CHEMOTHERAPY 28 (Supplement4), 242-255, 1980
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390282681259560832
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- NII論文ID
- 130004071510
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- NII書誌ID
- AN00186653
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- ISSN
- 18845894
- 00093165
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- NDL書誌ID
- 2221317
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可