書誌事項
- タイトル別名
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- LABORATORY AND CLINICAL STUDIES ON TICARCILLIN IN URINARY TRACT INFECTIONS
- ヒニョウキカ リョウイキ ニ オケル Ticarcillin ノ キソテキ リ
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抄録
1. Minimal inhibitory concentrations of ticarcillin, carbenicillin (CBPC) and sulbenicillin (SBPC) were determined by the plate dilution method against 48 strains of Ps. aeruginosa isolated from infected urine.<BR>In vitro antibacterial activities of ticarcillin varied with inoculum size. Its activities with 106 cells/ml inoculum size were more potent than 108 cells/ml. With 106 cells/ml of inoculum size, ticarcillin was 2 to 4 times more active than CBPC or SBPC against Ps. aeruginosa, 28 out of 48 strains (58.3%) being inhibited by concentration of 50 μg/ml or less.<BR>2. Ticarcillin was administered parenterally at a dose of 1 g twice a day for 7 days to 10 patients with chronic urinary tract infection.<BR>Results obtained were good in 5 cases, fair in 1 case and poor in 4 cases. The medication was well tolerated with no side effects.
収録刊行物
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- CHEMOTHERAPY
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CHEMOTHERAPY 25 (9), 2755-2760, 1977
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390282681259804800
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- NII論文ID
- 130004071149
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- NII書誌ID
- AN00186653
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- ISSN
- 18845894
- 00093165
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- NDL書誌ID
- 1914885
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可