複雑性慢性尿路感染症に対するTicarcillinの臨床的検討

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  • CLINICAL EXPERIENCE OF TICARCILLIN IN COMPLICATED CHRONIC URINARY TRACT INFECTION
  • フクザツセイ マンセイ ニョウロ カンセンショウ ニ タイスル Ticarci

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The therapeutic efficacy of ticarcillin has been evaluated in 28 cases (33 strains) with complicated chronic urinary tract infection.<BR>Ticarcillin was administrated by intramuscular injection for 2 to 10 days at a daily dose of 2 to 4 g.<BR>Some effects were obtained in 21 cases, of which 11 cases showed remarkable effect.<BR>Organisms isolated from patients were first Pseudomonas aeruginosa (15 strains), followed by 4 Citrobacter, 4 Klebsiella, 3 Proteus mirabilis, 2 E. coli and 4 other groups.<BR>In spite of high MIC against Pseudomonas, clinical effect of ticarcillin was especially good : Some effect was observed in 14 strains among 15 strains, and remarkable effect in 6 cases of them.<BR>As the side effect, one patient had severe pain at injected site and one had exanthema respectively after intramuscular administration of ticarcillin.

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