Ticarcillin (TIPC) の臨床的検討

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  • CLINICAL EVALUATION OF TICARCILLIN (TIPC)
  • Ticarcillin TIPC ノ リンショウテキ ケントウ

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Ticarcillin (TIPC) was evaluated in clinical trials and the following results were obtained.<BR>1. The MICs of ticarcillin were superior 1 to 2 steps to that of CBPC againstPs. aeruginosa, Proteus spp., Klebsiella andE. coli.<BR>2. Ticarcillin was administered to 11 patients with severe underlying disease in the department of internal medicine. As the result, ticarcillin showed good response in 4, fair in 4 and poor in 3 cases.<BR>3.Ps. aeruginosa was eradicated in 5 of 6 strains and as a whole, the bacteriological effect was seen in 10 strains of 13 isolated organisms.<BR>4. No side effects were seen and abnormal values in liver and renal functions were thought to be due to underlying disease.<BR>5. Recurrent cases were often seen. So, ticarcillin will be a useful antibiotic if dosage, medication and combined therapy with other antibiotics will be taken into consideration.

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