EXPERIMENTAL AND CLINICAL INVESTIGATION WITH MEZLOCILLIN IN URINARY TRACT INFECTION

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  • 尿路感染症に対するMezlocillinの検討
  • ニョウロ カンセンショウ ニ タイスル Mezlocillin ノ ケントウ

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Abstract

1. Mezlocillin was administered intravenously to 22 patients with urinary tract infections, in a dose of 2 g t. i. d., for 7 days. The results were as follows:<BR>2) As to the clinical results; In 2 patients with acute pyelonephritis, good in all cases. In 20 patients with complicated lower urinary tract infections, excellent in 1, good in 9 and poor in 10 cases, the overall effective rate was 50%.<BR>3. Bacteriologically, as a whole, 15 out of 22 strains were eliminated at the end of the treatment. The elimination rate was 68%. Among 15 strains eradicated, 10 were E. coil, 2 were Proteus, and 1 strain of Klebsiella, Pseudomonas and Staphylococcus, respectively.<BR>4. Slight elevation of transaminase, GOT, GPT in 1 and GPT in one case, was obsereved. No other side effect was reported or noticed.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 27 (Supplement1), 281-286, 1979

    Japanese Society of Chemotherapy

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