THE CILINICAL EXPERIMENT OF ATAT-2266 IN EXTERNAL EYE DISEASES AND THE PENETRATION INTO THE TEAR OF HUMAN EYES
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- TOKUDA HISAYA
- Department of Ophthalmology, Kyorin University, School of Medicine
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- ARIMOTO KEIZO
- Department of Ophthalmology, Kyorin University, School of Medicine
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- SHIMIZU CHIHIRO
- Department of Ophthalmology, Kyorin University, School of Medicine
Bibliographic Information
- Other Title
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- 眼科領域におけるAT-2266の臨床的・実験的検討
Abstract
14 cases of external eye diseases (Meibomitis, lacrimal canaliculitis and keratits) were cured all after 3-9 days (100%).<BR>The penetration of ATAT-2266 into the tear and the serum of 22 human cases were examined simultaneously at 0.25, 0.5, 1, 2, 3, 4, 6 and 8 hour after the oral administration of 200mg.<BR>The peak of tear level was 0.769±0.116μg/ml (1/ 2 hour after) and half time was 4 hours. This level was considered effective to the external eye infections both by S. aureus and P. aeruginosa.
Journal
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- CHEMOTHERAPY
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CHEMOTHERAPY 32 (Supplement3), 1084-1087, 1984
Japanese Society of Chemotherapy
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Details 詳細情報について
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- CRID
- 1390282681260464640
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- NII Article ID
- 130004194332
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- ISSN
- 18845894
- 00093165
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed