CS-807 IN UROLOGICAL INFECTIONS
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- NISHIZAWA KAZUAKI
- Department of Urology, School of Medicine Tokai University
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- WATANABE JUN
- Department of Urology, School of Medicine Tokai University
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- MASUDA AIICHIRO
- Department of Urology, School of Medicine Tokai University
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- TANAKA MOTOAKI
- Department of Urology, School of Medicine Tokai University
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- NAKAJIMA NOBORU
- Department of Urology, School of Medicine Tokai University
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- MIYAKITA HIDESHI
- Department of Urology, School of Medicine Tokai University
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- SHIRAMIZU MIKI
- Department of Urology, School of Medicine Tokai University
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- KATSUOKA YOJI
- Department of Urology, School of Medicine Tokai University
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- KINOSHITA HIDECHIKA
- Department of Urology, School of Medicine Tokai University
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- KAWAMURA NOBUO
- Department of Urology, School of Medicine Tokai University
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- KAWASHIMA TOSHIFUMI
- Tokai University Tokyo Hospital
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- OKADA KEISHI
- Tokai University Tokyo Hospital
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- TANIKAWA KATSUMI
- Tokai University Oiso Hospital
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- MATSUSHITA KAZUO
- Tokai University Oiso Hospital
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- OHKOSHI MASAAKI
- Tokai University Oiso Hospital
Bibliographic Information
- Other Title
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- 尿路感染症に対するCS-807の臨床的検討
Abstract
CS-807 is characterized by a broad antibacterial spectrum, covering gram-positive and-negative bacteria, and stability to, β-lactamases.<BR>We used this compound in the treatment of 52 patients with urinary tract infection (UTI) to investigate the drug's efficacy, safety, and usefulness.<BR>CS-807 was administered to 24 patients with acute uncomplicated cystitis, 1 with gonorrheal urethritis and 27 with complicated UTI.<BR>Efficacy was generally evaluated according to the criteria of the Japanese UTI Committee.<BR>In cases of acute uncomplicated cystitis, efficacy was rated as excellent in eight cases and moderate in four, the efficacy rate being 100%.<BR>In cases of chronic complicated UTI, efficacy was excellent in 2, moderate in 6 and poor in 2 cases, the efficacy rate being 80%. All these cases met the Japanese UTI criteria.<BR>Of 52 treated cases, side-effects were noted in two, 1 each of diarrhea and formation of aphthae in the oral cavity. Abnormal clinical laboratory data due to CS-807 were not observed in any of the cases.<BR>In view of the above results, we consider CS-807 to be a useful compound for the treatment of urinary tract infections.
Journal
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- CHEMOTHERAPY
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CHEMOTHERAPY 36 (Supplement1), 744-752, 1988
Japanese Society of Chemotherapy
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Details 詳細情報について
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- CRID
- 1390282681261793280
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- NII Article ID
- 130004195985
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- ISSN
- 18845894
- 00093165
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed