尿路感染症, 男子性器感染症に対するNY-198の臨床的検討

DOI

書誌事項

タイトル別名
  • NY-198 IN UROLOGICAL AND URO-GENITAL INFECTIONS

抄録

NY-198 is a new antimicrobial agent of quinolone derivation which is characterized by a broad antibacterial spectrum, covering Gram-positive and -negative bacteria.<BR>We used the compound for the treatment of 27 patients with urinary tract or uro-genital infection to investigate its efficacy, safety, and usefulness.<BR>NY-198 was administered to 7 patients with acute uncomplicated cystitis, 13 with complicated UTI, and 7 with uro-genital infection. The drug's efficacy was evaluated using the Japanese UTI Drug Evaluation Criteria.<BR>In cases of acute uncomplicated cystitis, NY-198 efficacy was evaluated as excellent in 3 cases and moderate in 1, the efficacy rate being 100%. In cases of complicated UTI, NY-198 was evaluated as excellent in 5, moderate in 2, and poor in 3 cases, the efficacy rate being 70%. All these cases met the UTI criteria. In cases of uro-genital infection, efficacy was assessed by the physician as excellent in 2 cases, good in 4, and poor in 1 case.<BR>Of 27 patients treated, side-effects were noted in 1, who complained of slight dizziness. No abnormal clinical laboratory data due to NY-198 were observed.<BR>In view of the above results, we consider NY-198 a useful compound for the treatment of urinary tract and uro-genital infections.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ