A new thermo-sensitive hydrogel: Poly(ethylene oxide-dimethyl siloxane-ethylene oxide)/poly(N-isopropyl acrylamide) interpenetrating polymer networks I. Synthesis and characterization.

DOI 4 Citations 12 References
  • Mukae Katsuya
    Center for Controlled Chemical Delivery, Department of Pharmaceutics, University of Utah
  • Bae You Han
    Center for Controlled Chemical Delivery, Department of Pharmaceutics, University of Utah
  • Okano Teruo
    Tokyo Women’s Medical College, Institute of Biomedical Engineering
  • Kim Sung Wan
    Center for Controlled Chemical Delivery, Department of Pharmaceutics, University of Utah

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Description

Interpenetrating polymer networks (IPNs) composed of poly(ethylene oxide-dimethyl siloxane-ethylene oxide) (PEO-PDMS-PEO) ABA triblock copolymer and poly(N-isopropyl acrylamide) (PIPAAm) were synthesized. Transmission electron microscopy (TEM) and differential scanning calorimetry (DSC) studies of bulk IPNS revealed micro phase separation with partial phase mixing between two chemically independent networks. Aqueous equilibrium swelling curves were examined as a function of temperature. DSC thermograms of the swollen IPNS exhibited the same swelling transition temperature as that of PIPAAm, although the degree of swelling of IPNS was affected by polymer composition. These observations indicate that each network in the swollen IPNs exists independently and many have different morphology than the dried bulk state. The aqueous swelling-deswelling kinetics by temperature modulation of IPNs could be controlled by gel composition nd temperatures applied.

Journal

  • Polymer Journal

    Polymer Journal 22 (3), 206-217, 1990

    The Society of Polymer Science, Japan

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Details 詳細情報について

  • CRID
    1390282681267252608
  • NII Article ID
    130004768164
  • DOI
    10.1295/polymj.22.206
  • COI
    1:CAS:528:DyaK3cXkt1ClsLo%3D
  • ISSN
    13490540
    00323896
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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