Cushing′s Syndrome Associated with Corticogenic Hypothyroidism:A Case Study

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  • INADA MITSUO
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • KURATA SHUNICHIRO
    Department of Internal Medicine, Shingu City Hospital
  • NISHIKAWA MITSUSHIGE
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • OISHI MARIKO
    Department of Internal Medicine, Kyoto National Hospital
  • MASHIO YASUO
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • TANAKA KIYOSHI
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • ISHII HITOSHI
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • NAITO KOICHI
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine
  • IMURA HIROO
    Second Division, Department of Internal Medicine, Kyoto University School of Medicine

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タイトル別名
  • Cushing's syndrome associated with corticogenic hypothyroidism: A case study.
  • Cushing s Syndrome Associated with Cort

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説明

Described here is a 27-year-old female, who had centripetal obesity, broad reddishpurple striae on the lower abdomen and hypertension. Serum cortisol levels, the results of a dexamethasone suppression test and an adrenal scintigram with 131I-19-iodocholesterol were all compatible with Cushing's syndrome due to an adrenal adenoma that secretes cortisol autonomously. This was confirmed by gross and microscopic examination of the removed adrenal tumor. In addition, the patient had markedly diminished T4 and T3 concentrations in serum. Basal TSH levels were not elevated and did not rise significantly after TRH injection. Serum T4 and T3 concentrations were elevated to the normal range when the hyperadrenocorticism was corrected. The results indicate that the patient had “corticogenic hypothyroidism.”.

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