Preventive Effect of an Aqueous Extract of Salacia reticulata on Hyperlipidemia in Rats.
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- Shimoda Hiroshi
- Research and Development Division, Morishita Jintan Co., Ltd.
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- Kawamori Shusuke
- Research and Development Division, Morishita Jintan Co., Ltd.
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- Kawahara Yuzo
- Research and Development Division, Morishita Jintan Co., Ltd.
Bibliographic Information
- Other Title
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- サラシア・レティキュラータ(Salacia reticulata)水抽出物のラットにおける高脂血症予防作用
- サラシア レティキュラータ Salacia reticulata ミズ チュウシュツブツ ノ ラット ニ オケル コウシケツショウ ヨボウ サヨウ
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Abstract
Effects of an aqueous extract from Salacia reticulata (SE), which has potent α-glucosidase inhibitory activity, on serum lipid levels in rats were investigated. Serum triglyceride (TG) in rats given a commercial diet containing 0.05 or 0.1% SE for 3 weeks was decreased. SE (0.1%) also suppressed the increase of serum and liver TG, but slightly increased the serum total and HDL-cholesterol (Cho) and liver Cho in rats given a high sucrose diet for 8 weeks. In rats fed a high-Cho diet for 1 week, SE (0.05, 0.1%) had no significant effects on the serum TG and Cho levels, but decreased the liver TG dose-dependently. Moreover, SE had no effect on the serum TG elevation in olive oil-loaded rats. These results confirmed that consecutive ingestion of SE lowered the serum TG level, and this activity appeared to be due to a decrease of absorbed sugars, which are the source of TG in vivo.
Journal
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- Nippon Eiyo Shokuryo Gakkaishi
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Nippon Eiyo Shokuryo Gakkaishi 53 (4), 149-154, 2000
Japan Society of Nutrition and Food Science
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Details 詳細情報について
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- CRID
- 1390282681268036352
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- NII Article ID
- 10009714654
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- NII Book ID
- AN00311992
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- COI
- 1:CAS:528:DC%2BD3cXmsVeqtbc%3D
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- ISSN
- 18832849
- 02873516
- http://id.crossref.org/issn/02873516
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- NDL BIB ID
- 5464811
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed