Effect of High Dietary Magnesium on Fecal Steroid Excretion in Rats.

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  • MIURA Tsutomu
    Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture
  • UEHARA Mariko
    Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture
  • SUZUKI Kazuharu
    Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture
  • GOTO Shiro
    Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture

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  • 高マグネシウム投与がラットの糞便中ステロイド排せつに及ぼす影響
  • コウ マグネシウム トウヨ ガ ラット ノ フンベンチュウ ステロイド ハイセ

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The effect of dietary magnesium levels on fecal steroid excretion was examined in 4-week-old male rats. We studied rats fed two levels of magnesium (0.05 and 0.2g/100g diet with a 5.0% dietary lipid content. It was found that increasing the level of magnesium in the diet produced on increase in body weight. The daily fecal weight was not influenced by dietary magnesium supplementation, but the fecal water content was increased. The daily fecal excretion of total lipids, cholesterol and bile acids was decreased, but the absorption rate of calcium, magnesium and phosphorus was not influenced by dietary magnesium supplementation. The serum total cholesterol, triglyceride and phospholipid levels were unaffected by dietary magnesium supplementation. These results suggest that high dietary magnesium intake does not inhibit absorption of total lipids, cholesterols and bile acids in the gastrointestinal tract.

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