Effects of Short-term Feeding of Triolein, Tripalmitin, Tristearin and Trilinolein on Serum Lipids and Lipoproteins in Healthy Young Woman.

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  • トリオレイン，トリパルミチン，トリステアリンおよびトリリノレインがヒト脂質代謝に及ぼす影響
  • トリオレイン トリパルミチン トリステアリン オヨビ トリリノレイン ガ ヒト

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A metabolic study was conducted to elucidate the effect of a diet enriched with various fatty acids in the form of triglycerides on serum lipids and lipoproteins in young women. The study was divided into two feeding periods of 5 days each, separated by a 7-day free diet period. Twelve healthy young women were divided into two groups, A (n=6) and B (n=6). The subjects in group A were fed a high-fat diet cooked with 60g/d triolein during the first period, and with 30 g/d tristearin during the second period. The subjects in group B were fed 60g/d trilinolein during the first period, and 30g/d tripalmitin during the second period. As well as the test fat, 10g/d beef tallow was added to the diet of both study groups during the second period to increase the test fatty acids and palatability of the test diet. The results obtained were as follows: 1) Significant decreases in mean serum total cholesterol, apo AI, AII and B, and LDL-cholesterol, -triglyceride and -phospholipids were observed after intake of the triolein or trilinolein diet. The serum HDL-cholesterol level was not affected by either diet. 2) The tristearin diet produced significant decreases in serum total cholesterol, LDL- and HDL-cholesterol, and apo AI and apo B. 3) The serum total and LDL-cholesterol levels were not affected by the tripalmitin diet, but the levels of HDL-cholesterol and apo AI were decreased significantly. The results of our short-term metabolic study suggest that the tested fatty acids do not increase the level of serum lipid when supplied in the form of triglyceride.

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