摂取カゼインレベルが腎臓および尿中のカルシウム量に及ぼす影響

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  • Effects of Dietary Protein Levels on Kidney and Urinary Calcium in Female Rats.
  • セッシュ カゼインレベル ガ ジンゾウ オヨビ ニョウチュウ ノ カルシウムリ

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An experiment was carried out to determine the effect of dietary protein levels on urinary calciun excretion, and the calcium contents of the kidney, serum and femur in female rats. Casein was the protein source, and the protein content in the diet was 10% (C-10), 20% (C-20) or 40% (C-40). Fischer-strain rats 4 weeks of age were fed one of the experimental diets for 5 weeks.<BR>The serum parathyroid hormone (PTH) level was also measured. The degree of enlargement and pathological features of the kidney were observed. The results obtained were as follows: 1) The C-40 group exhibited a higher level of urinary Ca excretion. 2) Enlargement of the kidney was recognized in the C-10 and C-40 groups. 3) The kidney Ca content in the C-10 group was significantly higher than in the other groups. 4) The serum ultrafiltrable Ca content in the C-40 group was lower than in the other groups. 5) The serum PTH content in the C-40 group was higher than in the other groups. These results indicate that the dietary protein level may influence Ca metabolism in the kidney.

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